Hidradenoma papilliferum is a benign tumor that usually occurs in the female anogenital region. It is benign tissue not cancerous but is often confused clinically with carcinoma of the vulva because of. The case was evaluated for malignancy, with the initial histopathology showing extensive squamous metaplasia but ultimately found to have hp. Although this lesion is frequently encountered in the pediatric population, sp can occur at any age. Lower power view of another case of hidradenoma papilliferum showing papillary and cystic areas in a collagenous stroma. He told me not to worry that he was sure it was nothing. Papillary hidradenoma is also known as hidradenoma papilliferum, is an uncommon lesion which. The lesion contained cells with papillary folds, tubules, cystically dilated spaces, and lumen lined by columnar cells with decapitation secretion, compatible with hidradenoma papilliferum hp figures 2 and 3. It is usually very small and asymptomatic, and to make a correct diagnosis is. In some cases the tumor displays a histopathology similar to syringocystadenoma papilliferum since they are closely related tumors which. Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary like glands. Histopathology following surgical removal indicated it represented a.
Papillary hidradenoma article about papillary hidradenoma. Currently, there are no known methods to prevent hidradenoma papilliferum of vulva occurrence. A papillary hidradenoma, also hidradenoma papilliferum, is a sharply circumscribed nodule or benign tumor of the apocrine gland usually found on the labia majora or the interlabial folds. Hidradenoma papilliferum is a benign cystic tumor originated in apocrine sweat glands of. Most cases of hidradenocarcinoma papilliferum originate from a preexisting hidradenoma papilliferum, and the anogenital region is the most common location. This large tendon based mass was clinically suspected to represent a giant cell tumor of the tendon sheath. Hidradenoma papilliferum is a rare tumor that occurs almost exclusively in females on the anogenital area.
Pdf on jun 1, 2018, rogerio nabor kondo and others published ectopic hidradenoma papilliferum find, read and cite all the research you. Mri characteristics of the lesion were atypical for this diagnosis. Hidradenoma papilliferum is a relatively common benign sweat gland neoplasm that arises almost exclusively in the anogenital region of women. Microscopically, in addition to classic histopathological features. Hidradenoma papilliferum is a slowgrowing benign skinadnexal tumor. Rarely these tumours are found on the trunk, the lower extremities, ear canal and eyelid. Read papillary cystadenoma of the lower lipmimicking hidradenoma papilliferum, journal of cutaneous pathology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. The lesions usually present as an asymptomatic slowgrowing, red, firm, mobile, welldelimitated nodule that grows for a long time before resection. From the departments of pathology drs leeborg and gatter. Histopathologically, hidradenocarcinoma papilliferum shows an appearance reminiscent of hidradenoma papilliferum, with papillary formations composed of a central core of fibrovascular tissue lined by a double layer of epithelial cells. Hidradenoma papilliferum hp is an uncommon benign cutaneous adnexal neoplasm of the anogenital region commonly seen in middleaged, caucasian females. They can be clinically confused with other lesions that can appear in this area such as malignancies and less frequently other benign neoplasms, such as lipomas, papillary hidradenoma, and epidermoid cysts 1. Hidradenoma papilliferum is a benign tumour of apocrine sweat glands. Cylindroma dermal cylindroma syringocystadenoma papilliferum papillary hidradenoma hidrocystoma apocrine gland carcinoma apocrine nevus.
How can hidradenoma papilliferum of vulva be prevented. Diagnostic pitfalls in syringocystadenocarcinoma papilliferum. Histologically, hidradenoma papilliferum is a circumscribed cystic dermal lesion filled. Each presented clinically with a small, solitary tumor in the anogenital region.
Hidradenoma papilliferum is a wellcircumscribed dermal nodule, usually without connection to the overlying epidermis figure 1. It has characteristic histopathological features composed of. Tubules and broad, elongated fronds form an arborizing pattern and are lined with a doublelayered epithelium figures 2, 3. Skin nonmelanocytic tumor hidradenoma papilliferum. Syringocystadenoma papilliferum on the chest is rare. The american journal of dermatopathology, 34 1, 104109. Nodular hidradenoma, also known as eccrine acrospiroma, is a benign adnexal skin tumour. All hidradenoma papilliferum messages cancercompass. The endocrine glands, or ductless glands, discharge their secretions hormones directly into the blood. Hidradenoma papilliferum, he 10x 1990 hidradenoma papilliferum, he 40x 1994 another case, he and antibody against smooth muscle actin. It has characteristic histopathological features composed of anastomosing and branching tubules, lined by columnar cells, and a basal layer of myoepithelial cells. Clear cell hidradenoma, solid and cystic hidradenoma or dermal acrospiromas. It usually presents as an asymptomatic fleshcolored nodule in the anogenital area of women.
Histopathologically, hidradenocarcinoma papilliferum shows an appearance reminiscent of hidradenoma papilliferum, with papillary formations composed of a central core of fibrovascular. Hidradenoma papilliferum is a rare benign cystic and papillary neoplasm. They can be clinically confused with other lesions that can appear in this area such as malignancies and less frequently other benign neoplasms, such as lipomas, papillary hidradenoma, and. Hidradenoma papilliferum, also called papillary hidradenoma, is benign tumour arising from apocrine glands see sweat gland lesions. Reported here are 18 cases of hidradenoma papilliferum with oxyphilic metaplasia. This was a small cyst on my vulvar i had it for about 1 year before my gyno decided it was not going away on its own and should be removed. Pathology of syringocystadenoma papilliferum dr sampurna. Like other cystic skin lesions, it often clinically presents as a skincolored nodule. Hidradenoma papilliferum is an uncommon benign cutaneous adnexal tumour arising from apocrine sweat glands with predilection to the vulvar area in middleaged women 35, 36. I have just been diagnosed with hidradenoma papilliferum.
It is then referred to as ectopic hidradenoma papilliferum. Syringocystadenoma papilliferum of the external ear. Hidradenoma papilliferum with mixed histopathologic features of. He had had a subcutaneous tumor on his right eyebrow for 30 years. Hidradenoma papilliferum hp is a benign, cystic, papillary apocrine gland tumor that occurs almost exclusively in women in anogenital region 1. Department of pathology, maharashtra institute of medical education and research. In addition, a single lesion may contain a mixture of celltypes. Pathology of syringocystadenoma papilliferum dr sampurna roy md. Solitary, nodule often partly solid, partly cystic. Hidradenoma papilliferum is a rare benign cystic tumor that originates from apocrine glands or anogenital mammary glands. Syringocystadenoma papilliferum is an uncommon benign tumor of disputed histogenesis, 667 with a predilection for the scalp and forehead. Nirmala d, rajnish k, sunita s, nidhi r 2011 hidradenoma papilliferum of the vulva. Papillary hidradenoma, vulva, he 40x 5982 hidradenoma papilliferum, sma 40x 5986. Sep 28, 2018 hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammarylike glands.
Hidradenoma papilliferum hp is a rare, small, benign, cystic, papillary, slow growing tumor occurring in anogenital region of adult women. Media in category histopathology of papillary hidradenoma the following 10 files are in this category, out of 10 total. Hidradenoma papilliferum of the vulva presenting as a. Soepronos textbook is available on and includes detailed information on over 600 entities and includes four dvd diskettes with highresolution images that provide a virtual dermatopathology reference and guide. It is benign tissue not cancerous but is often confused clinically with carcinoma of the vulva because of its tendency to ulcerate. The clinical characteristics of this tumor may be confusing, since it is uncommon. Hidradenoma papilliferum hp is a benign cutaneous adnexal neoplasm occurring mainly in the anogenital region of adult women and has features analogous to intraductal papilloma of the breast. Hidradenoma definition of hidradenoma by medical dictionary.
The lesion is a small solitary dermal or subcutaneous nodule, most commonly on the vulva histology of hidradenoma papilliferum. Here, we describe 2 cases of hidradenoma papilliferum of the anus. Hidradenoma papilliferum is a rare benign tumor of apocrine glands. Hidradenoma papilliferum is a benign cystic tumor, predominant in women aged 3050 years. Papillary hidradenoma, also hidradenoma papilliferum. Hidradenoma papilliferum with oncocytic metaplasia. Interlaboratory comparison of estrogen receptor analysis in parayn sections by a monoclonal antibody to estrophilin h222. What is the prognosis of hidradenoma papilliferum of vulva. A cytomorphological evaluation on fine needle aspiration cytology jitendra g nasit 1, gauravi dhruva 2 1 department of pathology, government medical college and sir sayajirao general hospital, baroda, gujarat, india 2 department of pathology, pandit deendayal upadhyay government medical college and hospital, rajkot, gujarat, india. Two female patients aged 39 and 35 presented with perianal masses with hemorrhoids. Only a single case of ductal carcinoma in situ arising in hp has been previously reported. Anastomosing and branching tubules, lined by columnar cells, and a basal layer of myoepithelial cells are the characteristic histopathological features.
Hidradenoma papilliferum with a ductal carcinoma in situ com. This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment. Syringocystadenoma papilliferum is an adnexal tumour which commonly occurs on the scalp, forehead or face. Hidradenoma papilliferum histopathology this feature is not available right now. Hidradenoma papilliferum of the vulva with extensive. Hidradenoma papilliferum with a ductal carcinoma in situ. Histopathology revealed a dermal tumor with no connection to the overlying epidermis.
Two female patients aged 39 and 35 presented with perianal masses. We describe a case of an 26yearold man that presented. Dec 31, 2019 hidradenoma papilliferum is a rare benign cystic tumor that originates from apocrine glands or anogenital mammary glands. Hidradenoma papilliferum article about hidradenoma. Cooper and mac donald, in 1944, described the first case of perianal hidradenoma papilliferum 2. A rare case of hidradenoma papilliferum journal of.
Most often, it presents as a raised warty plaque and is associated with alopecia when on the scalp. Sialadenoma papilliferum is a rare salivary gland tumor clinically resembling papilloma originating probably from the excretory duct. Hidradenoma papilliferum of the vulva with extensive squamous. The histological study shows a hidradenoma papilliferum. A case report from a tertiary hospital of rajasthan, india. A case of hidradenoma papilliferum with mixed features of syringocystadenoma papilliferum scap and anogenital mammary. Rare cases of ectopic nongenital hidradenoma papilliferum have been described. All patients were women ranging in age from 29 to 74 years. Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammarylike glands. Also known as papillary hidradenoma benign, small, sharply circumscribed nodule covered by normal skin, often on labia majora or interlabial folds may ulcerate through skin and simulate carcinoma may derive from ectopic mammary tissue resembles intraductal papilloma. Hidradenoma papilliferum of the vulva pubmed central pmc. A 32yearold female patient presented with an asymptomatic nodule of 4 months duration in the vulva. Hidradenoma papilliferum is a benign cutaneous adnexal neoplasm, commonly occurring in the vulva and perianal region of adult women. Cysts clinical images are available in hardcopy only.
Glands are divided into two main groups, endocrine and exocrine. It is characterized by a biphasic growth pattern of exophytic squamous component and endophytic glandular component. The patients underwent hemorrhoidectomy and excision of the lesion. Cytology, histopathology, hidradenocarcinoma, inguinal mass, metastasis.
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